BDBM746801 Synthesis of 8-(4-(tert-butoxy)-4-oxobutanamido)quinoline-4-carboxylic acid::US20250177582, Compound 8

SMILES N#C[C@@H]1CC(F)(F)CN1C(=O)CNC(=O)c1ccnc2c(NC(=O)CCC(=O)O)cccc12

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 746801   

TargetProlyl endopeptidase FAP(Human)
Philochem

US Patent
LigandPNGBDBM746801(Synthesis of 8-(4-(tert-butoxy)-4-oxobutanamido)qu...)
Affinity DataIC50: 10.9nMAssay Description:Inhibition assay of FAP. The compounds were precisely weighed (range between 20-1000 pg) on a micro-scale (HuberLab, Sartorius QUINTIX35-1S) and diss...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2025
Entry Details
US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

US Patent
LigandPNGBDBM746801(Synthesis of 8-(4-(tert-butoxy)-4-oxobutanamido)qu...)
Affinity DataIC50: 16.1nMAssay Description:Inhibition assay of FAP. The compounds were precisely weighed (range between 20-1000 pg) on a micro-scale (HuberLab, Sartorius QUINTIX35-1S) and diss...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2025
Entry Details
US Patent