BDBM746810 1.3.8.1 Synthesis of Compound 11::US20250177582, Compound 11

SMILES CN(C)C(=N)NCCC[C@H](NC(=O)CCC(=O)Nc1cccc2c(C(=O)NCC(=O)N3CC(F)(F)C[C@H]3C#N)ccnc12)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)O

InChI Key

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 746810   

TargetProlyl endopeptidase FAP(Human)
Philochem

US Patent
LigandPNGBDBM746810(1.3.8.1 Synthesis of Compound 11 | US20250177582, ...)
Affinity DataIC50: 0.156nMAssay Description:Inhibition assay of FAP. The compounds were precisely weighed (range between 20-1000 pg) on a micro-scale (HuberLab, Sartorius QUINTIX35-1S) and diss...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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Date in BDB:
9/30/2025
Entry Details
US Patent