BDBM746990 US20250179047, Example 160

SMILES Cc1c(C(=O)N(c2ccc(O)cc2)c2cc(C#N)n(C(F)F)c2C)cc(-c2cc3c(cc2C(=O)N2Cc4ccccc4C[C@H]2CN2CCCCC2)CN(C(=O)Cc2ccc(OCCN4CCN(C)CC4)cc2F)CC3)n1C

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 746990   

TargetApoptosis regulator Bcl-2(Human)
Les Laboratoires Servier

US Patent
LigandPNGBDBM746990(US20250179047, Example 160)
Affinity DataKi:  0.0300nMAssay Description:The assay was performed in a 40 μL volume in white 384-standard well plates (Corning #3574). An 11-point serial dilution of each compound was prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2025
Entry Details
US Patent

TargetApoptosis regulator Bcl-2 [D103Y](Human)
Les Laboratoires Servier

US Patent
LigandPNGBDBM746990(US20250179047, Example 160)
Affinity DataKi:  0.180nMAssay Description:The assay was performed in a 40 μL volume in white 384-standard well plates (Corning #3574). An 11-point serial dilution of each compound was prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2025
Entry Details
US Patent

TargetApoptosis regulator Bcl-2 [G101V](Human)
Les Laboratoires Servier

US Patent
LigandPNGBDBM746990(US20250179047, Example 160)
Affinity DataKi:  0.200nMAssay Description:The assay was performed in a 40 μL volume in white 384-standard well plates (Corning #3574). An 11-point serial dilution of each compound was prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2025
Entry Details
US Patent

TargetBcl-2-like protein 1(Human)
Les Laboratoires Servier

US Patent
LigandPNGBDBM746990(US20250179047, Example 160)
Affinity DataKi:  1.5nMAssay Description:The assay was performed in a 40 μL volume in white 384-standard well plates (Corning #3574). An 11-point serial dilution of each compound was prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2025
Entry Details
US Patent