BDBM747192 (6,7-dichloro-1,3,4,5-tetrahydro-2H-pyrido[4,3-b]indol-2-yl)(5- morpholinopyrimidin-2-yl)methanone::US20250179079, Compound 31

SMILES O=C(c1ncc(N2CCOCC2)cn1)N1CCc2[nH]c3c(Cl)c(Cl)ccc3c2C1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 747192   

TargetCyclic GMP-AMP synthase(Human)
Ventus Therapeutics U.S.

US Patent
LigandPNGBDBM747192((6,7-dichloro-1,3,4,5-tetrahydro-2H-pyrido[4,3-b]i...)
Affinity DataIC50: 222nMAssay Description:Certain compounds of the present disclosure were tested for their h-cGAS inhibition activity using the methodology reported in Lama et al., “Developm...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2025
Entry Details
US Patent