BDBM747208 (S)-(6,7-dichloro-1-methyl-1,3,4,5-tetrahydro-2H-pyrido[4,3-b]indol-2-yl)(5- methoxypyrimidin-2-yl)methanone::US20250179079, Compound 45B

SMILES COc1cnc(C(=O)N2CCc3[nH]c4c(Cl)c(Cl)ccc4c3[C@@H]2C)nc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 747208   

TargetCyclic GMP-AMP synthase(Human)TBA
LigandPNGBDBM747208((S)-(6,7-dichloro-1-methyl-1,3,4,5-tetrahydro-2H-p...)
Affinity DataIC50: 37.4nMAssay Description:Certain compounds of the present disclosure were tested for their h-cGAS inhibition activity using the methodology reported in Lama et al., “Developm...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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Date in BDB:
TBA
Entry Details
US Patent