BDBM747237 (6,7-dichloro-9-(1-methyl-1H-pyrazol-3-yl)-1,3,4,5-tetrahydro-2H-pyrido[4,3- b]indol-2-yl)(5-methoxypyrimidin-2-yl)methanone::US20250179079, Compound 71

SMILES COc1cnc(C(=O)N2CCc3[nH]c4c(Cl)c(Cl)cc(-c5ccn(C)n5)c4c3C2)nc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 747237   

TargetCyclic GMP-AMP synthase(Human)TBA
LigandPNGBDBM747237((6,7-dichloro-9-(1-methyl-1H-pyrazol-3-yl)-1,3,4,5...)
Affinity DataIC50: 133nMAssay Description:Certain compounds of the present disclosure were tested for their h-cGAS inhibition activity using the methodology reported in Lama et al., “Developm...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent