BDBM747241 (S)-(6,7-dichloro-1-methyl-1,3,4,5-tetrahydro-2H-pyrido[4,3-b]indol-2-yl)(5-(2- hydroxyethoxy)pyrimidin-2-yl)methanone::US20250179079, Compound 77B

SMILES C[C@H]1c2c([nH]c3c(Cl)c(Cl)ccc23)CCN1C(=O)c1ncc(OCCO)cn1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 747241   

TargetCyclic GMP-AMP synthase(Human)TBA
LigandPNGBDBM747241((S)-(6,7-dichloro-1-methyl-1,3,4,5-tetrahydro-2H-p...)
Affinity DataIC50: 32nMAssay Description:Certain compounds of the present disclosure were tested for their h-cGAS inhibition activity using the methodology reported in Lama et al., “Developm...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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Date in BDB:
TBA
Entry Details
US Patent