BDBM747256 WO-2019/153002, TDI-005685::1-(6,7-dichloro-1,3,4,5-tetrahydro-2H-pyrido[4,3-b]indol-2- yl)-2-hydroxyethan-1-one::US20250179079, Comparative Example A

SMILES O=C(CO)N1CCc2[nH]c3c(Cl)c(Cl)ccc3c2C1

InChI Key

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 747256   

TargetCyclic GMP-AMP synthase(Human)TBA
LigandPNGBDBM747256(WO-2019/153002, TDI-005685 | 1-(6,7-dichloro-1,3,4...)
Affinity DataIC50: 146nMAssay Description:Certain compounds of the present disclosure were tested for their h-cGAS inhibition activity using the methodology reported in Lama et al., “Developm...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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Date in BDB:
TBA
Entry Details
US Patent