BDBM747260 WO-2020/186027, Compound 67::1-(7,8-dichloro-10-(1-methyl-1H-pyrazol-3-yl)-3,4- dihydropyrazino[1,2-b]indazol-2(1H)-yl)-2-hydroxyethan-1- one::US20250179079, Comparative Example D

SMILES Cn1ccc(-c2cc(Cl)c(Cl)c3nn4c(c23)CN(C(=O)CO)CC4)n1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 747260   

TargetCyclic GMP-AMP synthase(Human)
Ventus Therapeutics U.S.

US Patent
LigandPNGBDBM747260(WO-2020/186027, Compound 67 | 1-(7,8-dichloro-10-(...)
Affinity DataIC50: 27.3nMAssay Description:Certain compounds of the present disclosure were tested for their h-cGAS inhibition activity using the methodology reported in Lama et al., “Developm...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2025
Entry Details
US Patent