BDBM747261 (S)-1-(7,8-dichloro-1-methyl-3,4-dihydropyrazino[1,2- b]indazol-2(1H)-yl)-2-hydroxyethan-1-one::US20250179079, Example 60B

SMILES C[C@H]1c2c3ccc(Cl)c(Cl)c3nn2CCN1C(=O)CO

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 747261   

TargetCyclic GMP-AMP synthase(Human)
Ventus Therapeutics U.S.

US Patent
LigandPNGBDBM747261((S)-1-(7,8-dichloro-1-methyl-3,4-dihydropyrazino[1...)
Affinity DataIC50: 82.8nMAssay Description:Certain compounds of the present disclosure were tested for their h-cGAS inhibition activity using the methodology reported in Lama et al., “Developm...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2025
Entry Details
US Patent