BDBM747272 12 1-(2-(4-(2-(6-Methylpyridin-2-yl)-6,7- dihydro-5H-pyrrolo[1,2-a]imidazol-3- yl)pyridin-2-yl)-4,6- dihydropyrrolo[3,4-d]imidazol-5(1H)- yl)propan-2-ol::US20250179094, Compound 12::US20250215017, Compound 12

SMILES Cc1cccc(-c2nc3n(c2-c2ccnc(-c4nc5c([nH]4)CN(CC(C)O)C5)c2)CCC3)n1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 747272   

TargetTGF-beta receptor type-1(Human)
Medinno Pharmaceutical Technology (Zhuhai) Co.

US Patent
LigandPNGBDBM747272(12 1-(2-(4-(2-(6-Methylpyridin-2-yl)-6,7- dihydro-...)
Affinity DataIC50: 4.30nMAssay Description:The principle of the activity assay was that TGFβR1 phosphorylates the substrate TGFβR1tide, consuming ATP in the process. This experiment employed t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Medinno Pharmaceutical Technology (Zhuhai) Co.

US Patent
LigandPNGBDBM747272(12 1-(2-(4-(2-(6-Methylpyridin-2-yl)-6,7- dihydro-...)
Affinity DataIC50: 4.30nMAssay Description:The principle of the activity assay was that TGFβR1 phosphorylates the substrate TGFβR1tide, consuming ATP in the process. This experiment employed t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/26/2025
Entry Details
US Patent