BDBM747276 22 (2-(4-(1-Isopropyl-3-(6- methylpyridin-2-yl)-1H-pyrazol-4- yl)pyridin-2-yl)-4,6- dihydropyrrolo[3,4-d]imidazol- 5(1H)-yl)(4-methylpiperazin-1- yl)ketone::US20250179094, Compound 22::US20250215017, Compound 22

SMILES Cc1cccc(-c2nn(C(C)C)cc2-c2ccnc(-c3nc4c([nH]3)CN(C(=O)N3CCN(C)CC3)C4)c2)n1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 747276   

TargetTGF-beta receptor type-1(Human)
Medinno Pharmaceutical Technology (Zhuhai) Co.

US Patent
LigandPNGBDBM747276(22 (2-(4-(1-Isopropyl-3-(6- methylpyridin-2-yl)-1H...)
Affinity DataIC50: 7.5nMAssay Description:The principle of the activity assay was that TGFβR1 phosphorylates the substrate TGFβR1tide, consuming ATP in the process. This experiment employed t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/26/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Medinno Pharmaceutical Technology (Zhuhai) Co.

US Patent
LigandPNGBDBM747276(22 (2-(4-(1-Isopropyl-3-(6- methylpyridin-2-yl)-1H...)
Affinity DataIC50: 7.5nMAssay Description:The principle of the activity assay was that TGFβR1 phosphorylates the substrate TGFβR1tide, consuming ATP in the process. This experiment employed t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2025
Entry Details
US Patent