BDBM747293 44 3-(3-(6-Methylpyridin-2-yl)-4-(2- (1,4,5,6-tetrahydropyrrolo[3,4- d]imidazol-2-yl)pyridin-4-yl)-1H- pyrazol-1-yl)propan-2-ol::US20250179094, Compound 44::US20250215017, Compound 44

SMILES Cc1cccc(-c2nn(CC(C)O)cc2-c2ccnc(-c3nc4c([nH]3)CNC4)c2)n1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 747293   

TargetTGF-beta receptor type-1(Human)
Medinno Pharmaceutical Technology (Zhuhai) Co.

US Patent
LigandPNGBDBM747293(44 3-(3-(6-Methylpyridin-2-yl)-4-(2- (1,4,5,6-tetr...)
Affinity DataIC50: 6.20nMAssay Description:The principle of the activity assay was that TGFβR1 phosphorylates the substrate TGFβR1tide, consuming ATP in the process. This experiment employed t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/26/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Medinno Pharmaceutical Technology (Zhuhai) Co.

US Patent
LigandPNGBDBM747293(44 3-(3-(6-Methylpyridin-2-yl)-4-(2- (1,4,5,6-tetr...)
Affinity DataIC50: 6.20nMAssay Description:The principle of the activity assay was that TGFβR1 phosphorylates the substrate TGFβR1tide, consuming ATP in the process. This experiment employed t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2025
Entry Details
US Patent