BDBM747297 48 2-[4-(1-Benzyl-3-(6-methylpyridin-2- yl)-1H-pyrazol-4-yl)pyridin-2-yl]-5- (methylsulfonyl)-1,4,5,6- tetrahydropyrrolo[3,4-d]imidazole::US20250179094, Compound 48::US20250215017, Compound 48

SMILES Cc1cccc(-c2nn(Cc3ccccc3)cc2-c2ccnc(-c3nc4c([nH]3)CN(S(C)(=O)=O)C4)c2)n1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 747297   

TargetTGF-beta receptor type-1(Human)
Medinno Pharmaceutical Technology (Zhuhai) Co.

US Patent
LigandPNGBDBM747297(48 2-[4-(1-Benzyl-3-(6-methylpyridin-2- yl)-1H-pyr...)
Affinity DataIC50: 1.60nMAssay Description:The principle of the activity assay was that TGFβR1 phosphorylates the substrate TGFβR1tide, consuming ATP in the process. This experiment employed t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Medinno Pharmaceutical Technology (Zhuhai) Co.

US Patent
LigandPNGBDBM747297(48 2-[4-(1-Benzyl-3-(6-methylpyridin-2- yl)-1H-pyr...)
Affinity DataIC50: 1.60nMAssay Description:The principle of the activity assay was that TGFβR1 phosphorylates the substrate TGFβR1tide, consuming ATP in the process. This experiment employed t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/26/2025
Entry Details
US Patent