BDBM747298 49 3-((3-(6-Methylpyridin-2-yl)-4-(2-(5- (methylsulfonyl)-1,4,5,6- tetrahydropyrrolo[3,4-d]imidazol-2- yl)pyridin-4-yl)- 1H-pyrazol-1- yl)methyl)cyclobutanol::US20250179094, Compound 49::US20250215017, Compound 49

SMILES Cc1cccc(-c2nn(CC3CC(O)C3)cc2-c2ccnc(-c3nc4c([nH]3)CN(S(C)(=O)=O)C4)c2)n1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 747298   

TargetTGF-beta receptor type-1(Human)
Medinno Pharmaceutical Technology (Zhuhai) Co.

US Patent
LigandPNGBDBM747298(49 3-((3-(6-Methylpyridin-2-yl)-4-(2-(5- (methylsu...)
Affinity DataIC50: 3nMAssay Description:The principle of the activity assay was that TGFβR1 phosphorylates the substrate TGFβR1tide, consuming ATP in the process. This experiment employed t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Medinno Pharmaceutical Technology (Zhuhai) Co.

US Patent
LigandPNGBDBM747298(49 3-((3-(6-Methylpyridin-2-yl)-4-(2-(5- (methylsu...)
Affinity DataIC50: 3nMAssay Description:The principle of the activity assay was that TGFβR1 phosphorylates the substrate TGFβR1tide, consuming ATP in the process. This experiment employed t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/26/2025
Entry Details
US Patent