BDBM747301 52 5-(Ethylsulfonyl)-2-[4-(1-methyl-3-(6- methylpyridin-2-yl)-1H-pyrazol-4- yl)pyridin-2-yl]-1,4,5,6- tetrahydropyrrolo[3,4-d]imidazole::US20250179094, Compound 52::US20250215017, Compound 52

SMILES CCS(=O)(=O)N1Cc2nc(-c3cc(-c4cn(C)nc4-c4cccc(C)n4)ccn3)[nH]c2C1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 747301   

TargetTGF-beta receptor type-1(Human)
Medinno Pharmaceutical Technology (Zhuhai) Co.

US Patent
LigandPNGBDBM747301(52 5-(Ethylsulfonyl)-2-[4-(1-methyl-3-(6- methylpy...)
Affinity DataIC50: 2.10nMAssay Description:The principle of the activity assay was that TGFβR1 phosphorylates the substrate TGFβR1tide, consuming ATP in the process. This experiment employed t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Medinno Pharmaceutical Technology (Zhuhai) Co.

US Patent
LigandPNGBDBM747301(52 5-(Ethylsulfonyl)-2-[4-(1-methyl-3-(6- methylpy...)
Affinity DataIC50: 2.10nMAssay Description:The principle of the activity assay was that TGFβR1 phosphorylates the substrate TGFβR1tide, consuming ATP in the process. This experiment employed t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/26/2025
Entry Details
US Patent