BDBM747323 74 N-Ethyl-N-methyl-2-(4-(2-(6- methylpyridin-2-yl)-5,6-dihydro-4H- pyrrolo[1,2-b]pyrazol-3-yl)pyridin-2- yl)-4,6-dihydropyrrolo[3,4- d]imidazole-5(1H)-carboxamide::US20250179094, Compound 74::US20250215017, Compound 74

SMILES CCN(C)C(=O)N1Cc2nc(-c3cc(-c4c(-c5cccc(C)n5)nn5c4CCC5)ccn3)[nH]c2C1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 747323   

TargetTGF-beta receptor type-1(Human)
Medinno Pharmaceutical Technology (Zhuhai) Co.

US Patent
LigandPNGBDBM747323(74 N-Ethyl-N-methyl-2-(4-(2-(6- methylpyridin-2-yl...)
Affinity DataIC50: 1.70nMAssay Description:The principle of the activity assay was that TGFβR1 phosphorylates the substrate TGFβR1tide, consuming ATP in the process. This experiment employed t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/26/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Medinno Pharmaceutical Technology (Zhuhai) Co.

US Patent
LigandPNGBDBM747323(74 N-Ethyl-N-methyl-2-(4-(2-(6- methylpyridin-2-yl...)
Affinity DataIC50: 1.70nMAssay Description:The principle of the activity assay was that TGFβR1 phosphorylates the substrate TGFβR1tide, consuming ATP in the process. This experiment employed t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2025
Entry Details
US Patent