BDBM747600 US12325697, Compound AJW-1

SMILES CN(Cc1cc2c(c(C(F)(F)F)c1)CN(c1cc(-c3c(-c4nncn4C)cnn3C)cc(C3CC3)n1)C2=O)CC1(O)CCC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 747600   

LigandPNGBDBM747600(US12325697, Compound AJW-1)
Affinity DataIC50: 200nMAssay Description:Fluorescein-BODIPY labeled UBED2D(C85K)-Ub was prepared by conjugating ubiquitin (Ub) labeled at its N-terminus with Fluorescein-BODIPY maleimide (Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/4/2025
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase CBL-C [47-435](Human)
Nimbus Clio

US Patent
LigandPNGBDBM747600(US12325697, Compound AJW-1)
Affinity DataIC50: 200nMAssay Description:Recombinant human c-Cbl (aa 47-435) was expressed in E. coli, purified and biotinylated in vitro. The protein was diluted to 12 nM in freshly prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/4/2025
Entry Details
US Patent