BDBM748312 US20250186450, Example 19

SMILES CC[C@@H]5CN(c2cc1nncn1c3c2nc(C)n3C[C@@H]4CCCO4)[C@@H](C)CN5C(c6ccc(Cl)cc6)C7CC(F)(F)C7

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 748312   

TargetDiacylglycerol kinase zeta(Human)
Incyte

US Patent
LigandPNGBDBM748312(US20250186450, Example 19)
Affinity DataIC50: 20nMAssay Description:The DGKα and DGKζ biochemical reactions were performed using His-tagged human recombinant enzymes (Signal Chem, DGKα, #D21-10BH; DGKζ, #D30-10H)) and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetDiacylglycerol kinase alpha(Human)
Incyte

US Patent
LigandPNGBDBM748312(US20250186450, Example 19)
Affinity DataIC50: 20nMAssay Description:The DGKα and DGKζ biochemical reactions were performed using His-tagged human recombinant enzymes (Signal Chem, DGKα, #D21-10BH; DGKζ, #D30-10H)) and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent