BDBM748622 (NB011692-080-002): 2-(2-cyanophenoxy)-2,2-difluoro-N-((3S,4S)-3-methylpiperidin-4-yl)acetamide::US20250188037, Example 33

SMILES C[C@H]1CNCC[C@@H]1NC(=O)C(F)(F)Oc1ccccc1C#N

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 748622   

TargetSomatostatin receptor type 4(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM748622((NB011692-080-002): 2-(2-cyanophenoxy)-2,2-difluor...)
Affinity DataIC50: 162nMAssay Description:Test compounds are suspended in DMSO and then diluted in assay buffer (25 mM HEPES pH 7.4, 10 mM MgCl2, 1 mM CaCl2, 0.5% BSA) plus 0.2 nM I-125 label...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetSomatostatin receptor type 1(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM748622((NB011692-080-002): 2-(2-cyanophenoxy)-2,2-difluor...)
Affinity DataIC50: 5.01E+4nMAssay Description:Test compounds are suspended in DMSO and then diluted in assay buffer (25 mM HEPES pH 7.4, 10 mM MgCl2, 1 mM CaCl2, 0.5% BSA) plus 0.4 nM I-125 label...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent