BDBM748708 4-((1-(4- chlorophenyl)pyrrolidin-3- yl)methoxy)-2- cyclopropylpyrimidine-5- carbonitrile::US20250188057, Compound 57

SMILES N#Cc1cnc(C2CC2)nc1OCC1CCN(c2ccc(Cl)cc2)C1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 748708   

TargetCeramide glucosyltransferase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM748708(4-((1-(4- chlorophenyl)pyrrolidin-3- yl)methoxy)-2...)
Affinity DataIC50: 20nMAssay Description:Using Promega's UDP-Glo™ Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measured by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent