BDBM748731 methyl (S)-2-(6-((1-(5-cyano-2- cyclopropylpyrimidin-4-yl)azetidin-3- yl)oxy)-2,3-dihydrobenzofuran-3- yl)acetate::US20250188057, Compound 80

SMILES COC(=O)C[C@@H]1COc2cc(OC3CN(c4nc(C5CC5)ncc4C#N)C3)ccc21

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 748731   

TargetCeramide glucosyltransferase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM748731(methyl (S)-2-(6-((1-(5-cyano-2- cyclopropylpyrimid...)
Affinity DataIC50: 303nMAssay Description:Using Promega's UDP-Glo™ Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measured by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent