BDBM748740 4-((1S,4S)-5-(4-chlorobenzyl)-2,5- diazabicyclo[2.2.1]heptan-2-yl)-2- cyclopropylpyrimidine-5-carbonitrile::US20250188057, Compound 89

SMILES N#Cc1cnc(C2CC2)nc1N1C[C@@H]2C[C@H]1CN2Cc1ccc(Cl)cc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 748740   

TargetCeramide glucosyltransferase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM748740(4-((1S,4S)-5-(4-chlorobenzyl)-2,5- diazabicyclo[2....)
Affinity DataIC50: 352nMAssay Description:Using Promega's UDP-Glo™ Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measured by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent