BDBM748753 2-cyclopropyl-4-((5- phenyltetrahydrofuran-2- yl)methoxy)pyrimidin-5-carbonitrile::US20250188057, Compound 102

SMILES N#Cc1cnc(C2CC2)nc1OCC1CCC(c2ccccc2)O1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 748753   

TargetCeramide glucosyltransferase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM748753(2-cyclopropyl-4-((5- phenyltetrahydrofuran-2- yl)m...)
Affinity DataIC50: 195nMAssay Description:Using Promega's UDP-Glo™ Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measured by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent