BDBM748778 Preparation of(S)-4-azaspiro[2.5]octan-6-amine::US20250188059, Example 1

SMILES Nc3ncc(c2cc(c1cnn(CC(F)(F)F)c1)ncc2F)nc3C(=O)NC4CCCNC4

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 748778   

TargetSerine/threonine-protein kinase Chk2(Human)
Arum Therapeutics

US Patent
LigandPNGBDBM748778(Preparation of(S)-4-azaspiro[2.5]octan-6-amine | U...)
Affinity DataIC50: 55nMAssay Description:The compounds of Examples 1 to 66 were diluted at various concentrations and transferred to a 384-well plate by 5 μl, and 10 μl of a mixed solution (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent