BDBM748782 (S)-3-amino-6-(2-(1-(2-hydroxy-2- methylpropyl)-1H-pyrazol-4- yl)pyridin-4-yl)-N-(piperidin-3-yl) pyrazine-2-carboxamide::US20250188059, Example 5

SMILES CC(C)(O)Cn1cc(-c2cc(-c3cnc(N)c(C(=O)NC4CCCNC4)n3)ccn2)cn1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 748782   

TargetSerine/threonine-protein kinase Chk2(Human)
Arum Therapeutics

US Patent
LigandPNGBDBM748782((S)-3-amino-6-(2-(1-(2-hydroxy-2- methylpropyl)-1H...)
Affinity DataIC50: 10nMAssay Description:The compounds of Examples 1 to 66 were diluted at various concentrations and transferred to a 384-well plate by 5 μl, and 10 μl of a mixed solution (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent