BDBM748792 3-amino-N-((3S,5S)-5- fluoropiperidin-3-yl)-6-(2-(1-(2,2,2- trifluoroethyl)-1H-pyrazol-4- yl)pyridin-4-yl)pyrazine-2-carboxamide::US20250188059, Example 15

SMILES Nc3ncc(c2ccnc(c1cnn(CC(F)(F)F)c1)c2)nc3C(=O)N[C@@H]4CNC[C@@H](F)C4

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 748792   

TargetSerine/threonine-protein kinase Chk2(Human)
Arum Therapeutics

US Patent
LigandPNGBDBM748792(3-amino-N-((3S,5S)-5- fluoropiperidin-3-yl)-6-(2-(...)
Affinity DataIC50: 10nMAssay Description:The compounds of Examples 1 to 66 were diluted at various concentrations and transferred to a 384-well plate by 5 μl, and 10 μl of a mixed solution (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Arum Therapeutics

US Patent
LigandPNGBDBM748792(3-amino-N-((3S,5S)-5- fluoropiperidin-3-yl)-6-(2-(...)
Affinity DataIC50: 550nMAssay Description:The compounds of Examples 1 to 66 were diluted at various concentrations and transferred to a 384-well plate by 5 μl, and 10 μl of a mixed solution (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent