BDBM748797 (S)-3-amino-6-(2-(1-cyclopropyl-1H- pyrazol-4-yl)pyridin-4-yl)-N- (piperidin-3-yl)pyrazine-2-carboxamide::US20250188059, Example 20

SMILES Nc1ncc(-c2ccnc(-c3cnn(C4CC4)c3)c2)nc1C(=O)NC1CCCNC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 748797   

TargetSerine/threonine-protein kinase Chk2(Human)
Arum Therapeutics

US Patent
LigandPNGBDBM748797((S)-3-amino-6-(2-(1-cyclopropyl-1H- pyrazol-4-yl)p...)
Affinity DataIC50: 55nMAssay Description:The compounds of Examples 1 to 66 were diluted at various concentrations and transferred to a 384-well plate by 5 μl, and 10 μl of a mixed solution (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Arum Therapeutics

US Patent
LigandPNGBDBM748797((S)-3-amino-6-(2-(1-cyclopropyl-1H- pyrazol-4-yl)p...)
Affinity DataIC50: 55nMAssay Description:The compounds of Examples 1 to 66 were diluted at various concentrations and transferred to a 384-well plate by 5 μl, and 10 μl of a mixed solution (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent