BDBM748800 3-amino-N-((3S,5S)-5- fluoropiperidin-3-yl)-6-(2-hydroxy-5- (1-(2,2,2-trifluoroethyl)-1H-pyrazol-4- yl)phenyl)pyrazine-2-carboxamide::US20250188059, Example 23

SMILES Nc3ncc(c2cc(c1cnn(CC(F)(F)F)c1)ccc2O)nc3C(=O)N[C@@H]4CNC[C@@H](F)C4

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 748800   

TargetSerine/threonine-protein kinase Chk2(Human)
Arum Therapeutics

US Patent
LigandPNGBDBM748800(3-amino-N-((3S,5S)-5- fluoropiperidin-3-yl)-6-(2-h...)
Affinity DataIC50: 10nMAssay Description:The compounds of Examples 1 to 66 were diluted at various concentrations and transferred to a 384-well plate by 5 μl, and 10 μl of a mixed solution (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent