BDBM748807 (S)-3-amino-6-(3-(1-(2-hydroxy-2- methylpropyl)-1H-pyrazol-4- yl)phenyl)-N-(piperidin-3-yl)pyrazine- 2-carboxamide::US20250188059, Example 30

SMILES CC(C)(O)Cn1cc(-c2cccc(-c3cnc(N)c(C(=O)N[C@H]4CCCNC4)n3)c2)cn1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 748807   

TargetSerine/threonine-protein kinase Chk2(Human)
Arum Therapeutics

US Patent
LigandPNGBDBM748807((S)-3-amino-6-(3-(1-(2-hydroxy-2- methylpropyl)-1H...)
Affinity DataIC50: 10nMAssay Description:The compounds of Examples 1 to 66 were diluted at various concentrations and transferred to a 384-well plate by 5 μl, and 10 μl of a mixed solution (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Arum Therapeutics

US Patent
LigandPNGBDBM748807((S)-3-amino-6-(3-(1-(2-hydroxy-2- methylpropyl)-1H...)
Affinity DataIC50: 55nMAssay Description:The compounds of Examples 1 to 66 were diluted at various concentrations and transferred to a 384-well plate by 5 μl, and 10 μl of a mixed solution (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent