BDBM748837 3-amino-6-(3-(5,5-dimethyl-5,6-dihydro- 4H-pyrrolo[1,2-b]pyrazol-3-yl)phenyl)-N- ((3R,4R)-4-hydroxypyrrolidin-3- yl)pyrazine-2-carboxamide::US20250188059, Example 60

SMILES CC1(C)Cc2c(-c3cccc(-c4cnc(N)c(C(=O)N[C@@H]5CNC[C@H]5O)n4)c3)cnn2C1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 748837   

TargetSerine/threonine-protein kinase Chk2(Human)
Arum Therapeutics

US Patent
LigandPNGBDBM748837(3-amino-6-(3-(5,5-dimethyl-5,6-dihydro- 4H-pyrrolo...)
Affinity DataIC50: 10nMAssay Description:The compounds of Examples 1 to 66 were diluted at various concentrations and transferred to a 384-well plate by 5 μl, and 10 μl of a mixed solution (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent