BDBM748847 2-(oxazol-5-yl)-N-(4-(7-(pyridin-2-yl)-5H-pyrrolo[2,3-b]pyrazin-6-yl)pyridin-2-yl)acetamide::US20250188075, Example 4

SMILES O=C(Cc1cnco1)Nc1cc(-c2[nH]c3cccnc3c2-c2ccccn2)ccn1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 748847   

TargetCasein kinase I isoform alpha(Human)
The Broad Institute

US Patent
LigandPNGBDBM748847(2-(oxazol-5-yl)-N-(4-(7-(pyridin-2-yl)-5H-pyrrolo[...)
Affinity DataIC50: 1.82nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into a white 1536-well microtiter plate (Greiner Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetCasein kinase I isoform delta(Human)
The Broad Institute

US Patent
LigandPNGBDBM748847(2-(oxazol-5-yl)-N-(4-(7-(pyridin-2-yl)-5H-pyrrolo[...)
Affinity DataIC50: 5.22nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into a white 1536-well microtiter plate (Greiner Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetCasein kinase I isoform alpha(Human)
The Broad Institute

US Patent
LigandPNGBDBM748847(2-(oxazol-5-yl)-N-(4-(7-(pyridin-2-yl)-5H-pyrrolo[...)
Affinity DataIC50: 47nMAssay Description:For the assay 50 nl of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a white low volume 384-well microtiter plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetCasein kinase I isoform gamma-3(Human)
The Broad Institute

US Patent
LigandPNGBDBM748847(2-(oxazol-5-yl)-N-(4-(7-(pyridin-2-yl)-5H-pyrrolo[...)
Affinity DataIC50: 50.3nMAssay Description:For the assay 50 nl of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a white 1536-well microtiter plate (Greiner Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent