BDBM748861 N-[4-[3-(2-pyridyl)-1H-pyrrolo[3,2-b]pyridin-2-yl]-2-pyridyl]-2-[1-(2,2,2-trifluoroethyl)pyrazol-3-yl]acetamide::US20250188075, Example 20

SMILES O=C(Cc1ccn(CC(F)(F)F)n1)Nc5cc(c3[nH]c2cccnc2c3c4ccccn4)ccn5

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 748861   

TargetCasein kinase I isoform alpha(Human)
The Broad Institute

US Patent
LigandPNGBDBM748861(N-[4-[3-(2-pyridyl)-1H-pyrrolo[3,2-b]pyridin-2-yl]...)
Affinity DataIC50: 1.88nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into a white 1536-well microtiter plate (Greiner Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetCasein kinase I isoform delta(Human)
The Broad Institute

US Patent
LigandPNGBDBM748861(N-[4-[3-(2-pyridyl)-1H-pyrrolo[3,2-b]pyridin-2-yl]...)
Affinity DataIC50: 4.93nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into a white 1536-well microtiter plate (Greiner Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetCasein kinase I isoform gamma-3(Human)
The Broad Institute

US Patent
LigandPNGBDBM748861(N-[4-[3-(2-pyridyl)-1H-pyrrolo[3,2-b]pyridin-2-yl]...)
Affinity DataIC50: 14.8nMAssay Description:For the assay 50 nl of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a white 1536-well microtiter plate (Greiner Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetCasein kinase I isoform alpha(Human)
The Broad Institute

US Patent
LigandPNGBDBM748861(N-[4-[3-(2-pyridyl)-1H-pyrrolo[3,2-b]pyridin-2-yl]...)
Affinity DataIC50: 98.7nMAssay Description:For the assay 50 nl of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a white low volume 384-well microtiter plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent