BDBM749095 (1R,3R)-3-[3- [(2S)-2-(3,4- difluorophenyl) propyl]-8- (methoxycarbonyl)- 3H,6H,7H,8H, 9H-imidazo[4,5- h]isoquinolin- 2- yl]cyclohexane- 1-carboxylic acid::US20250188079, Compound 148

SMILES COC(=O)N1CCc2ccc3c(nc([C@@H]4CCC[C@@H](C(=O)O)C4)n3C[C@@H](C)c3ccc(F)c(F)c3)c2C1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 749095   

TargetCREB-binding protein(Human)
Forma Therapeutics

US Patent
LigandPNGBDBM749095((1R,3R)-3-[3- [(2S)-2-(3,4- difluorophenyl) propyl...)
Affinity DataIC50: 5.5nMAssay Description:The assay was performed in a final volume of 6 μL in assay buffer containing 50 mM Hepes (pH 7.5, (0.5M Hepes, pH 7.5 solution; Teknova H1575)), 0.5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent