BDBM749348 US20250188095, Example 7

SMILES Cc1nc(N2C[C@H]3CN(C(=O)c4c(-c5ncccc5F)cn5ccccc45)C[C@H]3C2)nc2ccoc12

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 749348   

TargetOrexin receptor type 2(Human)
Jiangsu Nhwa Pharmaceutical Co.

US Patent
LigandPNGBDBM749348(US20250188095, Example 7)
Affinity DataIC50: 650nMAssay Description:(1) Preparation of a reaction buffer (1×Stimulation buffer) required for the experiment: The 5×Stimulation buffer and ddH2O in the Cisbio IP-one kit ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Human)
Jiangsu Nhwa Pharmaceutical Co.

US Patent
LigandPNGBDBM749348(US20250188095, Example 7)
Affinity DataIC50: 1.00E+3nMAssay Description:(1) Preparation of a reaction buffer (1×Stimulation buffer) required for the experiment: The 5×Stimulation buffer and ddH2O in the Cisbio IP-one kit ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent