BDBM749351 (2-(3-Fluoropyridin-2-yl)indolizin-1-yl)((3aR,6aS)-5-(quinoxalin-2-yl)hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl)methanone::US20250188095, Example 10

SMILES O=C(c1c(-c2ncccc2F)cn2ccccc12)N1C[C@@H]2CN(c3cnc4ccccc4n3)C[C@@H]2C1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 749351   

TargetOrexin receptor type 2(Human)
Jiangsu Nhwa Pharmaceutical Co.

US Patent
LigandPNGBDBM749351((2-(3-Fluoropyridin-2-yl)indolizin-1-yl)((3aR,6aS)...)
Affinity DataIC50: 200nMAssay Description:(1) Preparation of a reaction buffer (1×Stimulation buffer) required for the experiment: The 5×Stimulation buffer and ddH2O in the Cisbio IP-one kit ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Human)
Jiangsu Nhwa Pharmaceutical Co.

US Patent
LigandPNGBDBM749351((2-(3-Fluoropyridin-2-yl)indolizin-1-yl)((3aR,6aS)...)
Affinity DataIC50: 1.00E+3nMAssay Description:(1) Preparation of a reaction buffer (1×Stimulation buffer) required for the experiment: The 5×Stimulation buffer and ddH2O in the Cisbio IP-one kit ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent