BDBM749363 (2-(3-fluoropyridin-2-yl)indolizin-1-yl)((3aR,6aS)-5-(4-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-2-yl)hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl)methanone::US20250188095, Example 26

SMILES Cc1nc(N2C[C@H]3CN(C(=O)c4c(-c5ncccc5F)cn5ccccc45)C[C@H]3C2)nc2c1CCC2

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 749363   

TargetOrexin receptor type 2(Human)
Jiangsu Nhwa Pharmaceutical Co.

US Patent
LigandPNGBDBM749363((2-(3-fluoropyridin-2-yl)indolizin-1-yl)((3aR,6aS)...)
Affinity DataIC50: 650nMAssay Description:(1) Preparation of a reaction buffer (1×Stimulation buffer) required for the experiment: The 5×Stimulation buffer and ddH2O in the Cisbio IP-one kit ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Human)
Jiangsu Nhwa Pharmaceutical Co.

US Patent
LigandPNGBDBM749363((2-(3-fluoropyridin-2-yl)indolizin-1-yl)((3aR,6aS)...)
Affinity DataIC50: 1.00E+3nMAssay Description:(1) Preparation of a reaction buffer (1×Stimulation buffer) required for the experiment: The 5×Stimulation buffer and ddH2O in the Cisbio IP-one kit ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent