BDBM749703 US12331038, Compound PF-06835919

SMILES C[C@H]1CCN1c1nc(N2C[C@@H]3C(CC(=O)O)[C@@H]3C2)cc(C(F)(F)F)n1

InChI Key

PDB links: 1 PDB ID matches this monomer.

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 749703   

TargetKetohexokinase(Human)TBA
LigandPNGBDBM749703(US12331038, Compound PF-06835919)
Affinity DataIC50: 7.07nMAssay Description:1) The present compounds and the control drug were formulated in DMSO to 10 mM as stock solutions for test.2) The stock solutions of the compounds of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
TBA
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetKetohexokinase(Human)TBA
LigandPNGBDBM749703(US12331038, Compound PF-06835919)
Affinity DataIC50: 9.5nMAssay Description:1) The present compounds and the control drug were formulated in DMSO to 10 mM as stock solutions for test.2) The stock solutions of the compounds of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
TBA
Entry Details
US Patent
PDB3D3D Structure (crystal)