BDBM749903 (S)-N-((S)-1-(4-chloro-5-(4- fluorophenyl)-1H-imidazol-2-yl)-7- (isoxazol-3-yl)-7-oxoheptyl)-6- methyl-6-azaspiro[2.5]octane-1- carboxamide 2,3- dihydroxysuccinate::US12331044, Example 195

SMILES CN1CCC2(CC1)C[C@@H]2C(=O)N[C@@H](CCCCCC(=O)c1ccon1)c1nc(Cl)c(-c2ccc(F)cc2)[nH]1

InChI Key InChIKey=SUNGABODFFTHQQ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 749903   

TargetHistone deacetylase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM749903((S)-N-((S)-1-(4-chloro-5-(4- fluorophenyl)-1H-imid...)
Affinity DataIC50: 0.140nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/9/2025
Entry Details
Go to US Patent

TargetHistone deacetylase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM749903((S)-N-((S)-1-(4-chloro-5-(4- fluorophenyl)-1H-imid...)
Affinity DataIC50: 0.320nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/9/2025
Entry Details
Go to US Patent

TargetHistone deacetylase 3(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM749903((S)-N-((S)-1-(4-chloro-5-(4- fluorophenyl)-1H-imid...)
Affinity DataIC50: 0.0460nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/9/2025
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM749903((S)-N-((S)-1-(4-chloro-5-(4- fluorophenyl)-1H-imid...)
Affinity DataIC50: 3.10E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/9/2025
Entry Details
Go to US Patent

TargetHistone deacetylase 8(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM749903((S)-N-((S)-1-(4-chloro-5-(4- fluorophenyl)-1H-imid...)
Affinity DataIC50: 9.60nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/9/2025
Entry Details
Go to US Patent