BDBM750389 US20250195475, Example 41

SMILES COC[C@H]1C[C@@H]1C(=O)Nc3cc([C@H]2CC[C@@H](OC(N)=O)C2)[nH]n3

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 750389   

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Inventisbio

US Patent
LigandPNGBDBM750389(US20250195475, Example 41)
Affinity DataIC50: 0.900nMAssay Description:Compound Preparation. Dissslove the compounds into DMSO solution to make 10 mM DMSO stock. Serially dilute the stock solution from highest concentrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Human)
Inventisbio

US Patent
LigandPNGBDBM750389(US20250195475, Example 41)
Affinity DataIC50: 254nMAssay Description:Compound Preparation. Dissslove the compounds into DMSO solution to make 10 mM DMSO stock. Serially dilute the stock solution from highest concentrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Inventisbio

US Patent
LigandPNGBDBM750389(US20250195475, Example 41)
Affinity DataIC50: 306nMAssay Description:Compound Preparation. Dissslove the compounds into DMSO solution to make 10 mM DMSO stock. Serially dilute the stock solution from highest concentrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Inventisbio

US Patent
LigandPNGBDBM750389(US20250195475, Example 41)
Affinity DataIC50: 572nMAssay Description:Compound Preparation. Dissslove the compounds into DMSO solution to make 10 mM DMSO stock. Serially dilute the stock solution from highest concentrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent