BDBM750992 US20250195521, Example A450

SMILES CCn1c(-c2cc(N3CCN(C)CC3)cnc2[C@H](C)OC)c2c3cc(ccc31)-c1csc(n1)C[C@H](NC(=O)[C@H](C(C)C)N(C)C(=O)[C@@H]1OCC[C@@H]1c1ccncc1)C(=O)N1CCC[C@H](N1)C(=O)OCC(C)(C)C2

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 750992   

TargetGTPase NRas [G12C](Human)
Revolution Medicines

US Patent
LigandPNGBDBM750992(US20250195521, Example A450)
Affinity DataIC50: 55nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetGTPase NRas [Q61R](Human)
Revolution Medicines

US Patent
LigandPNGBDBM750992(US20250195521, Example A450)
Affinity DataIC50: 55nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetGTPase NRas(Human)
Revolution Medicines

US Patent
LigandPNGBDBM750992(US20250195521, Example A450)
Affinity DataIC50: 55nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetGTPase KRas [Q61H](Human)
Revolution Medicines

US Patent
LigandPNGBDBM750992(US20250195521, Example A450)
Affinity DataIC50: 55nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetGTPase KRas [G12C](Human)
Revolution Medicines

US Patent
LigandPNGBDBM750992(US20250195521, Example A450)
Affinity DataIC50: 55nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetGTPase NRas [Q61K](Human)
Revolution Medicines

US Patent
LigandPNGBDBM750992(US20250195521, Example A450)
Affinity DataIC50: 55nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Revolution Medicines

US Patent
LigandPNGBDBM750992(US20250195521, Example A450)
Affinity DataIC50: 550nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

Targetkras g13d(Human)
Revolution Medicines

US Patent
LigandPNGBDBM750992(US20250195521, Example A450)
Affinity DataIC50: 550nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetGTPase KRas(Human)
Revolution Medicines

US Patent
LigandPNGBDBM750992(US20250195521, Example A450)
Affinity DataIC50: 550nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetGTPase KRas [G12V](Human)
Revolution Medicines

US Patent
LigandPNGBDBM750992(US20250195521, Example A450)
Affinity DataIC50: 550nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetGTPase KRas [G13C](Human)
Revolution Medicines

US Patent
LigandPNGBDBM750992(US20250195521, Example A450)
Affinity DataIC50: 550nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetGTPase KRas [G12V](Human)
Revolution Medicines

US Patent
LigandPNGBDBM750992(US20250195521, Example A450)
Affinity DataIC50: 550nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent