BDBM751216 US20250195521, Example A89b

SMILES CCn1c(-c2cnccc2COC)c2c3cc(ccc31)-c1cc(O)cc(c1)C[C@H](NC(=O)[C@H](C(C)C)N(C)C(=O)C1(O)COC1)C(=O)N1CCC[C@H](N1)C(=O)OCC(C)(C)C2

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 751216   

TargetGTPase KRas [G12C](Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 751216BDBM751216(US20250195521, Example A89b)
Affinity DataIC50: 34nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetGTPase KRas [G13C](Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 751216BDBM751216(US20250195521, Example A89b)
Affinity DataIC50: 580nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent