BDBM751248 N-(3-(4-(1-benzyl- 5-isopropoxy-1H- benzo[d]imidazol- 2-yl)-3- chlorophenoxy) propyl)acetamide::US20250195530, Example A3

SMILES CC(=O)NCCCOc1ccc(-c2nc3cc(OC(C)C)ccc3n2Cc2ccccc2)c(Cl)c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 751248   

TargetDNA polymerase theta(Human)
Astrazeneca

US Patent
LigandPNGBDBM751248(N-(3-(4-(1-benzyl- 5-isopropoxy-1H- benzo[d]imidaz...)
Affinity DataIC50: 2nMAssay Description:In the assay, Polθ interacts with the substrates (deoxy thymidine triphosphate (dTTP) (Sigma, product code T0251) and a DNA template with a 17-nucleo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent