BDBM751256 9-benzyl-6- isopropoxy- 8-(2- methyl-4- (2- (piperazin- 1-yl) ethoxy) phenyl)- 9H-purine::US20250195530, Example B2

SMILES CC(C)Oc1ncnc2c1nc(-c1ccc(OCCN3CCNCC3)cc1Cl)n2Cc1ccccc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 751256   

TargetDNA polymerase theta(Human)
Astrazeneca

US Patent
LigandPNGBDBM751256(9-benzyl-6- isopropoxy- 8-(2- methyl-4- (2- (piper...)
Affinity DataIC50: 2nMAssay Description:In the assay, Polθ interacts with the substrates (deoxy thymidine triphosphate (dTTP) (Sigma, product code T0251) and a DNA template with a 17-nucleo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent