BDBM751269 1-(4-((4- (9-benzyl-6-(1- methylcyclo- propoxy)-9H- purin-8-yl)-3- chlorophenoxy) methyl)piperidin- 1-yl)ethan-1-one::US20250195530, Example D1

SMILES CC(=O)N1CCC(COc2cc(Cl)c(-c3nc4c(OC5(C)CC5)ncnc4n3Cc3ccccc3)cn2)CC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 751269   

TargetDNA polymerase theta(Human)
Astrazeneca

US Patent
LigandPNGBDBM751269(1-(4-((4- (9-benzyl-6-(1- methylcyclo- propoxy)-9H...)
Affinity DataIC50: 2nMAssay Description:In the assay, Polθ interacts with the substrates (deoxy thymidine triphosphate (dTTP) (Sigma, product code T0251) and a DNA template with a 17-nucleo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent