BDBM751294 (R)-9- benzyl-8-(2- chloro-4- (piperidin-3- yloxy)phenyl)- 6-(1- methylcyclo- propoxy)-9H- purine::US20250195530, Example D32

SMILES CC1(Oc2ncnc3c2nc(-c2ccc(O[C@@H]4CCCNC4)cc2Cl)n3Cc2ccccc2)CC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 751294   

TargetDNA polymerase theta(Human)
Astrazeneca

US Patent
LigandPNGBDBM751294((R)-9- benzyl-8-(2- chloro-4- (piperidin-3- yloxy)...)
Affinity DataIC50: 2.51nMAssay Description:In the assay, Polθ interacts with the substrates (deoxy thymidine triphosphate (dTTP) (Sigma, product code T0251) and a DNA template with a 17-nucleo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent