BDBM751325 1-(4-(2-((5-(9- benzyl-6-(1- methylcyclopropoxy)- 9H-purin-8- yl)-4- methylpyridin-2- yl)oxy)ethyl) piperazin-1-yl)ethan- 1-one::US20250195530, Example G4

SMILES CC(=O)N1CCN(CCOc2cc(C)c(-c3nc4c(OC5(C)CC5)ncnc4n3Cc3ccccc3)cn2)CC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 751325   

TargetDNA polymerase theta(Human)
Astrazeneca

US Patent
LigandPNGBDBM751325(1-(4-(2-((5-(9- benzyl-6-(1- methylcyclopropoxy)- ...)
Affinity DataIC50: 2nMAssay Description:In the assay, Polθ interacts with the substrates (deoxy thymidine triphosphate (dTTP) (Sigma, product code T0251) and a DNA template with a 17-nucleo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent