BDBM751347 9-benzyl-8-(2,6- dimethyl-4-(2- (4- methylpiperazin- 1- yl)ethoxy) phenyl)- 6-(1- methyl- cyclopropoxy)- 9H-purine::US20250195530, Example H4

SMILES Cc1cc(OCCN2CCN(C)CC2)cc(C)c1-c1nc2c(OC3(C)CC3)ncnc2n1Cc1ccccc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 751347   

TargetDNA polymerase theta(Human)
Astrazeneca

US Patent
LigandPNGBDBM751347(9-benzyl-8-(2,6- dimethyl-4-(2- (4- methylpiperazi...)
Affinity DataIC50: 2nMAssay Description:In the assay, Polθ interacts with the substrates (deoxy thymidine triphosphate (dTTP) (Sigma, product code T0251) and a DNA template with a 17-nucleo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent