BDBM751349 9-benzyl-8-(2- bromo-4-(2-(4- methylpiperazin-1- yl)ethoxy)phenyl)- 6-(1- methyl- cyclopropoxy)- 9H-purine::US20250195530, Example H6

SMILES CN1CCN(CCOc2ccc(-c3nc4c(OC5(C)CC5)ncnc4n3Cc3ccccc3)c(Br)c2)CC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 751349   

TargetDNA polymerase theta(Human)
Astrazeneca

US Patent
LigandPNGBDBM751349(9-benzyl-8-(2- bromo-4-(2-(4- methylpiperazin-1- y...)
Affinity DataIC50: 2nMAssay Description:In the assay, Polθ interacts with the substrates (deoxy thymidine triphosphate (dTTP) (Sigma, product code T0251) and a DNA template with a 17-nucleo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent