BDBM751418 1-(2-(4-(9- benzyl-6-(1- methylcyclo- propoxy)- 9H-purin-8- yl)-3- chlorophenoxy) ethyl)-3,3- dimethyl- piperazin- 2-one::US20250195530, Example R16

SMILES CC1(Oc2ncnc3c2nc(-c2ccc(OCCN4CCNC(C)(C)C4=O)cc2Cl)n3Cc2ccccc2)CC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 751418   

TargetDNA polymerase theta(Human)
Astrazeneca

US Patent
LigandPNGBDBM751418(1-(2-(4-(9- benzyl-6-(1- methylcyclo- propoxy)- 9H...)
Affinity DataIC50: 2nMAssay Description:In the assay, Polθ interacts with the substrates (deoxy thymidine triphosphate (dTTP) (Sigma, product code T0251) and a DNA template with a 17-nucleo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent